Mary-Louise Parker & Jeffrey Dean Morgan Split

This is not the first time the pair have separated. They briefly split last June, but quickly rekindled their romance.

'Weeds' co-stars Mary-Louise Parker and Jeffrey Dean Morgan have broken off their engagement.
Parker, who plays a suburban marijuana dealer in the hit US TV show, is believed to have initiated the split from Morgan, who stars as the deceased husband of Parker's character in the series

According to a friend of the couple, the pair - who have been dating since 2006 - ran into problems because of their "differing lifestyles". However, the source stressed Parker, 43, still holds Morgan, 41, "in the highest regard and hopes they remain friends".

This is not the first time the pair have separated. They briefly split last June, but quickly rekindled their romance, before announcing their engagement in February.

Parker adopted a baby girl from Africa last September and also has a four-year-old son with actor Billy Crudup, who she dated for seven years. In 2003, Crudup left Parker when she was seven months pregnant with their baby.

Representatives for both Parker and Morgan have declined to comment on the split.